Reaction Details Report a problem with these data
Target
Trace amine-associated receptor 1
Ligand
BDBM50359499
Substrate
n/a
Meas. Tech.
ChEMBL_792740 (CHEMBL1930655)
EC50
920±n/a nM
Citation
 Lewin, AH; Miller, GM; Gilmour, B Trace amine-associated receptor 1 is a stereoselective binding site for compounds in the amphetamine class. Bioorg Med Chem 19:7044-8 (2011) [PubMed]  Article 
Target
Name:
Trace amine-associated receptor 1
Synonyms:
Trace amine receptor 1 (TARR1) | Trace amine-associated receptor1 | TAAR1_MOUSE | Taar1 | Ta1 | Tar1 | Trar1 | Trace amine-associated receptor 1 (TAAR1)
Type:
Protein
Mol. Mass.:
37635.41
Organism:
Mouse
Description:
Q923Y8
Residue:
332
Sequence:
MHLCHAITNISHRNSDWSREVQASLYSLMSLIILATLVGNLIVIISISHFKQLHTPTNWLLHSMAIVDFLLGCLIMPCSMVRTVERCWYFGEILCKVHTSTDIMLSSASIFHLAFISIDRYCAVCDPLRYKAKINISTILVMILVSWSLPAVYAFGMIFLELNLKGVEELYRSQVSDLGGCSPFFSKVSGVLAFMTSFYIPGSVMLFVYYRIYFIAKGQARSINRTNVQVGLEGKSQAPQSKETKAAKTLGIMVGVFLVCWCPFFLCTVLDPFLGYVIPPSLNDALYWFGYLNSALNPMVYAFFYPWFRRALKMVLLGKIFQKDSSRSKLFL
  
Inhibitor
Name:
BDBM50359499
Synonyms:
METHAMPHETAMINE | (S)Methamphetamine
Type:
Small organic molecule
Emp. Form.:
C10H15N
Mol. Mass.:
n/a
SMILES:
C[C@@H](Cc1ccccc1)NC
Structure:
Search PDB for entries with ligand similarity: