Reaction Details Report a problem with these data
Target
Prostaglandin E2 receptor EP2 subtype
Ligand
BDBM50156554
Substrate
n/a
Meas. Tech.
ChEMBL_795667 (CHEMBL1936148)
Ki
2500±n/a nM
Citation
 Kambe, T; Maruyama, T; Nakano, M; Nakai, Y; Yoshida, T; Matsunaga, N; Oida, H; Konaka, A; Maruyama, T; Nakai, H; Toda, M Discovery of a novel EP2/EP4 dual agonist with high subtype-selectivity. Bioorg Med Chem Lett 22:396-401 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP2 subtype
Synonyms:
Prostaglandin E2 | Prostaglandin E2 receptor EP2 subtype | PGE receptor, EP2 subtype | PE2R2_MOUSE | Ptger2 | Ptgerep2 | Prostanoid EP2 receptor
Type:
G-protein coupled receptor
Mol. Mass.:
40495.26
Organism:
Mouse
Description:
n/a
Residue:
362
Sequence:
MDNFLNDSKLMEDCKSRQWLLSGESPAISSVMFSAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESHACTYFAFTMTFFSLATMLMLFAMALERYLSIGYPYFYRRHLSRRGGLAVLPVIYGASLLFCSLPLLNYGEYVQYCPGTWCFIRHGRTAYLQLYATMLLLLIVAVLACNISVILNLIRMHRRSRRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAICSLPFTIFAYMDETSSLKEKWDLRALRFLSVNSIIDPWVFAILRPPVLRLMRSVLCCRTSLRTQEAQQTSCSTQSSASKQTDLCGQL
  
Inhibitor
Name:
BDBM50156554
Synonyms:
4-(2-((R)-2-((S,E)-3-hydroxyoct-1-enyl)-5-oxopyrrolidin-1-yl)ethylthio)butanoic acid | CHEMBL223151
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: