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Target
Prostaglandin E2 receptor EP3 subtype
Ligand
BDBM50142481
Substrate
n/a
Meas. Tech.
ChEMBL_795668 (CHEMBL1936149)
Ki
39±n/a nM
Citation
 Kambe, T; Maruyama, T; Nakano, M; Nakai, Y; Yoshida, T; Matsunaga, N; Oida, H; Konaka, A; Maruyama, T; Nakai, H; Toda, M Discovery of a novel EP2/EP4 dual agonist with high subtype-selectivity. Bioorg Med Chem Lett 22:396-401 (2011) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP3 subtype
Synonyms:
Prostaglandin E2 receptor EP3 isoform alpha | PGE receptor, EP3 isoform alpha | Prostaglandin E3 | PE2R3_MOUSE | Ptger3 | Ptgerep3 | Prostanoid EP3 receptor
Type:
G-protein coupled receptor
Mol. Mass.:
40092.50
Organism:
Mouse
Description:
n/a
Residue:
365
Sequence:
MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLSSLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWPGTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKAAVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKECNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWSDQLER
  
Inhibitor
Name:
BDBM50142481
Synonyms:
8-aza-11-deoxyprostaglandin E1 | 7-[(R)-2-((E)-(S)-3-Hydroxy-oct-1-enyl)-5-oxo-pyrrolidin-1-yl]-heptanoic acid | CHEMBL42027
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: