Reaction Details Report a problem with these data
Target
Amine oxidase [flavin-containing] B
Ligand
BDBM15579
Substrate
n/a
Meas. Tech.
ChEMBL_796758 (CHEMBL1938073)
IC50
17±n/a nM
Citation
 Serra, S; Ferino, G; Matos, MJ; Vázquez-Rodríguez, S; Delogu, G; Viña, D; Cadoni, E; Santana, L; Uriarte, E Hydroxycoumarins as selective MAO-B inhibitors. Bioorg Med Chem Lett 22:258-61 (2011) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
MAO-B | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) | AOFB_HUMAN | MAOB
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Human
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM15579
Synonyms:
US8633208, Deprenyl | CHEMBL972 | L-Deprenyl | SLG | DEPRENYL | methyl[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-ylamine | N-methyl-N-[(2R)-1-phenylpropan-2-yl]prop-2-yn-1-amine | Selegiline | US9469653, Selegiline
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: