Reaction Details Report a problem with these data
Target
Autoinducer 2-binding periplasmic protein LuxP
Ligand
BDBM50165862
Substrate
n/a
Meas. Tech.
ChEMBL_799867 (CHEMBL1941573)
EC50
32±n/a nM
Citation
 Rui, F; Marques, JC; Miller, ST; Maycock, CD; Xavier, KB; Ventura, MR Stereochemical diversity of AI-2 analogs modulates quorum sensing in Vibrio harveyi and Escherichia coli. Bioorg Med Chem 20:249-56 (2011) [PubMed]  Article 
Target
Name:
Autoinducer 2-binding periplasmic protein LuxP
Synonyms:
LUXP_VIBHA | luxP
Type:
PROTEIN
Mol. Mass.:
41453.75
Organism:
Vibrio harveyi
Description:
ChEMBL_1513759
Residue:
365
Sequence:
MKKALLFSLISMVGFSPASQATQVLNGYWGYQEFLDEFPEQRNLTNALSEAVRAQPVPLSKPTQRPIKISVVYPGQQVSDYWVRNIASFEKRLYKLNINYQLNQVFTRPNADIKQQSLSLMEALKSKSDYLIFTLDTTRHRKFVEHVLDSTNTKLILQNITTPVREWDKHQPFLYVGFDHAEGSRELATEFGKFFPKHTYYSVLYFSEGYISDVRGDTFIHQVNRDNNFELQSAYYTKATKQSGYDAAKASLAKHPDVDFIYACSTDVALGAVDALAELGREDIMINGWGGGSAELDAIQKGDLDITVMRMNDDTGIAMAEAIKWDLEDKPVPTVYSGDFEIVTKADSPERIEALKKRAFRYSDN
  
Inhibitor
Name:
BDBM50165862
Synonyms:
(4S)-4,5-dihydroxypentane-2,3-dione | (S)-4,5-dihydroxypentane-2,3-dione | 4,5-Dihydroxy-2,3-pentanedione | CHEMBL193493 | CHEMBL194166
Type:
Small organic molecule
Emp. Form.:
C5H8O4
Mol. Mass.:
132.1146
SMILES:
CC(O)C(=O)C(=O)CO
Structure:
Search PDB for entries with ligand similarity: