Reaction Details Report a problem with these data
Target
Eukaryotic translation initiation factor 4E
Ligand
BDBM50365100
Substrate
n/a
Meas. Tech.
ChEMBL_804895 (CHEMBL1953943)
IC50
16000±n/a nM
Citation
 Rydzik, AM; Kulis, M; Lukaszewicz, M; Kowalska, J; Zuberek, J; Darzynkiewicz, ZM; Darzynkiewicz, E; Jemielity, J Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety--fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis. Bioorg Med Chem 20:1699-710 (2012) [PubMed]  Article 
Target
Name:
Eukaryotic translation initiation factor 4E
Synonyms:
IF4E_RABIT | EIF4E
Type:
PROTEIN
Mol. Mass.:
25047.40
Organism:
Rabbit
Description:
ChEMBL_1511842
Residue:
217
Sequence:
MATVEPETTPTPNPPPAEEEKTESNQEVANPEHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQLSSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWLETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGRVYKERLGLPPKIVIGYQSHADTATKSGSTTKNRFVV
  
Inhibitor
Name:
BDBM50365100
Synonyms:
CHEMBL1951195
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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