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Target
Platelet-activating factor receptor
Ligand
BDBM50282015
Substrate
n/a
Meas. Tech.
ChEBML_155136
IC50
1000±n/a nM
Citation
 Whittaker, M; Thompson, TM; Spavold, ZM; Price, M; Miller, A; Galloway, W; Fraser, F; Floyd, CD; Drummond, AH; Davidson, AH; Bowles, SA; Bebbington, DS Cyclic ether acetal platelet activating factor (PAF) receptor antagonists I: 3-pyridyl derivatives Bioorg Med Chem Lett 3:1493-1498 (1993)    Article 
Target
Name:
Platelet-activating factor receptor
Synonyms:
PAF Platelet activating factor | PAF-R | PAFR | PTAFR | PTAFR_HUMAN | Platelet activating factor receptor | Platelet-activating factor receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39219.60
Organism:
Homo sapiens (Human)
Description:
PAF Platelet activating factor PTAFR HUMAN::P25105
Residue:
342
Sequence:
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLTMADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVTRPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKGSVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAVFIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKFRKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
  
Inhibitor
Name:
BDBM50282015
Synonyms:
(cis)-3-{3-[5-(4-Chloro-phenyl)-tetrahydro-furan-2-yloxy]-propyl}-pyridine | CHEMBL37603
Type:
Small organic molecule
Emp. Form.:
C18H20ClNO2
Mol. Mass.:
317.81
SMILES:
Clc1ccc(cc1)[C@H]1CC[C@@H](OCCCc2cccnc2)O1
Structure:
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