Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM50290020
Substrate
n/a
Meas. Tech.
ChEBML_212342
IC50
7200±n/a nM
Citation
 Salimbeni, A; Paleari, F; Canevotti, R; Criscuoli, M; Criscuoli, M; Lippi, A; Angiolini, M; Belvisi, L; Scolastico, C; Colombo, L Design and synthesis of conformationally constrained arginal thrombin inhibitors Bioorg Med Chem Lett 7:2205-2210 (1997)    Article 
Target
Name:
Serine protease 1
Synonyms:
Beta-Trypsin | Cationic trypsin | PRSS1 | TRP1 | TRY1 | TRY1_BOVIN | TRYP1 | Trypsin | Trypsin I
Type:
Enzyme
Mol. Mass.:
25790.52
Organism:
Bos taurus (bovine)
Description:
P00760
Residue:
246
Sequence:
MKTFIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLNSGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTLNNDIMLIKLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGSGCAQKNKPGVYTKVCNYVSWIKQTIASN
  
Inhibitor
Name:
BDBM50290020
Synonyms:
(S)-1-Phenylacetyl-pyrrolidine-2-carboxylic acid ((S)-1-formyl-4-guanidino-butyl)-amide | BMY-44621 | CHEMBL304794
Type:
Small organic molecule
Emp. Form.:
C19H27N5O3
Mol. Mass.:
373.4494
SMILES:
NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1C(=O)Cc1ccccc1)C=O
Structure:
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