Reaction Details Report a problem with these data
Target
D(3) dopamine receptor
Ligand
BDBM50290217
Substrate
n/a
Meas. Tech.
ChEBML_58772
Ki
2.5±n/a nM
Citation
 Belliotti, TR; Kesten, SR; Rubin, JR; Wustrow, DJ; Georgic, LM; Zoski, KT; Akunne, HC; Wise, LD Novel cyclohexyl amides as potent and selective D3 dopamine receptor ligands Bioorg Med Chem Lett 7:2403-2408 (1997)    Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50290217
Synonyms:
CHEMBL78916 | N-{4-[2-(4-Phenyl-piperazin-1-yl)-ethyl]-cyclohexyl}-acetamide
Type:
Small organic molecule
Emp. Form.:
C20H31N3O
Mol. Mass.:
329.4796
SMILES:
CC(=O)N[C@H]1CC[C@H](CCN2CCN(CC2)c2ccccc2)CC1 |wU:7.7,wD:4.3,(4.65,-12.02,;3.76,-10.79,;2.22,-10.79,;4.53,-9.46,;6.07,-9.45,;6.84,-10.78,;8.38,-10.76,;9.15,-9.43,;10.69,-9.43,;11.46,-8.1,;13,-8.06,;13.8,-9.36,;15.34,-9.34,;16.08,-8,;15.29,-6.68,;13.75,-6.72,;17.62,-7.96,;18.35,-6.63,;19.89,-6.59,;20.7,-7.91,;19.95,-9.26,;18.41,-9.29,;8.38,-8.1,;6.84,-8.12,)|
Structure:
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