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Target
5-hydroxytryptamine receptor 3B
Ligand
BDBM50013043
Substrate
n/a
Meas. Tech.
ChEBML_3121
Ki
10±n/a nM
Citation
 Rizzi, JP; Nagel, AA; Rosen, T; McLean, S; Seeger, T An initial three-component pharmacophore for specific serotonin-3 receptor ligands. J Med Chem 33:2721-5 (1990) [PubMed]  Article
Target
Name:
5-hydroxytryptamine receptor 3B
Synonyms:
Serotonin 3 receptor (5HT3) | Serotonin 3b (5-HT3b) receptor
Type:
PROTEIN
Mol. Mass.:
50317.35
Organism:
Mus musculus
Description:
ChEMBL_3121
Residue:
437
Sequence:
MILLWSCLLVAVVGILGTATPQPGNSSLHRLTRQLLQQYHKEVRPVYNWAEATTVYLDLCVHAVLDVDVQNQKLKTSVWYREVWNDEFLSWNSSLFDEIQEISLPLSALWAPDIIINEFVDVERSPDLPYVYVNSSGTIRNHKPIQVVSACSLQTYAFPFDIQNCSLTFNSILHTVEDIDLGFLRNREDIENDKRAFMNDSEWQLLSVSSTYHIRQSSAGDFAQIRFNVVIRRCPLAYVVSLLIPSIFLMLVDLGSFYLPPNCRARIVFKTNVLVGYTVFRVNMSDEVPRSAGCTPLIGVFFTVCMALLVLSLSKSILLIKFLYEERHSGQERPLMCLQGDSDAEESRLYLGAPRADVTESPVHQEHRVPSDTLKDFWFQFRSINNSLRTRDQIHQKEVEWLAILYRFDQLLFRIYLAVLGLYTVTLCSLWALWSRM
  
Inhibitor
Name:
BDBM50013043
Synonyms:
3-[2-(5-Methyl-1H-imidazol-4-ylmethyl)-thiazol-4-yl]-1H-indole | CHEMBL290938
Type:
Small organic molecule
Emp. Form.:
C16H14N4S
Mol. Mass.:
294.374
SMILES:
Cc1nc[nH]c1Cc1nc(cs1)-c1c[nH]c2ccccc12
Structure:
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