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Target
D(2) dopamine receptor
Ligand
BDBM50132693
Substrate
n/a
Meas. Tech.
ChEMBL_62407 (CHEMBL675732)
Ki
2.2±n/a nM
Citation
 Pettersson, I; Liljefors, T Conformational analysis of dopamine D-2 receptor antagonists of the benzamide series in relation to a recently proposed D-2 receptor-interaction model. J Med Chem 35:2355-63 (1992) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50132693
Synonyms:
4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide | 4-Amino-N-(1-benzyl-piperidin-4-yl)-5-chloro-2-methoxy-benzamide(Clebopride) | 4-amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide | CHEMBL325109 | Clebopride
Type:
Small organic molecule
Emp. Form.:
C20H24ClN3O2
Mol. Mass.:
373.876
SMILES:
COc1cc(N)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)CC1
Structure:
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