Target
Mu-type opioid receptor
Ligand
BDBM50032527
Substrate
n/a
Meas. Tech.
ChEMBL_145285 (CHEMBL752954)
Ki
1.4±n/a nM
Citation
 Schmidhammer, HJennewein, HKKrassnig, RTraynor, JRPatel, DBell, KFroschauer, GMattersberger, KJachs-Ewinger, CJura, P Synthesis and biological evaluation of 14-alkoxymorphinans. 11. 3-Hydroxycyprodime and analogues: opioid antagonist profile in comparison to cyprodime. J Med Chem 38:3071-7 (1995) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50032527
Synonyms:
17-cyclopropylmethyl-10-ethoxy-4-hydroxy-3-methoxy-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-13-one | CHEMBL317269
Type:
Small organic molecule
Emp. Form.:
C23H31NO4
Mol. Mass.:
385.4965
SMILES:
CCO[C@@]12CCC(=O)CC11CCN(CC3CC3)C2Cc2ccc(O)c(OC)c12 |TLB:2:3:27.19.18:12.10.11,24:27:3:12.10.11,13:12:3:27.19.18|
Structure:
Search PDB for entries with ligand similarity: