Reaction Details Report a problem with these data
Target
Diamine acetyltransferase 1
Ligand
BDBM50095431
Substrate
n/a
Meas. Tech.
ChEMBL_198445 (CHEMBL804767)
IC50
40000±n/a nM
Citation
 Casero, RA; Woster, PM Terminally alkylated polyamine analogues as chemotherapeutic agents. J Med Chem 44:1-26 (2001) [PubMed]  Article 
Target
Name:
Diamine acetyltransferase 1
Synonyms:
SAT | SAT1 | SAT1_HUMAN | Spermidine/spermine N(1)-acetyltransferase 1
Type:
PROTEIN
Mol. Mass.:
20017.22
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1337637
Residue:
171
Sequence:
MAKFVIRPATAADCSDILRLIKELAKYEYMEEQVILTEKDLLEDGFGEHPFYHCLVAEVPKEHWTPEGHSIVGFAMYYFTYDPWIGKLLYLEDFFVMSDYRGFGIGSEILKNLSQVAMRCRCSSMHFLVAEWNEPSINFYKRRGASDLSSEEGWRLFKIDKEYLLKMATEE
  
Inhibitor
Name:
BDBM50095431
Synonyms:
CHEMBL86940 | N-Ethyl-N'-[3-(3-prop-2-ynylamino-propylamino)-propyl]-propane-1,3-diamine(PENSpm)
Type:
Small organic molecule
Emp. Form.:
C14H30N4
Mol. Mass.:
254.4148
SMILES:
CCNCCCNCCCNCCCNCC#C
Structure:
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