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Target
Matrilysin
Ligand
BDBM50102482
Substrate
n/a
Meas. Tech.
ChEMBL_105037 (CHEMBL711551)
IC50
9870±n/a nM
Citation
 Pikul, S; Ohler, NE; Ciszewski, G; Laufersweiler, MC; Almstead, NG; De, B; Natchus, MG; Hsieh, LC; Janusz, MJ; Peng, SX; Branch, TM; King, SL; Taiwo, YO; Mieling, GE Potent and selective carboxylic acid-based inhibitors of matrix metalloproteinases. J Med Chem 44:2499-502 (2001) [PubMed]  Article 
Target
Name:
Matrilysin
Synonyms:
Matrix metalloproteinase 7 | Matrix metalloproteinase-7 (MMP-7) | MMP7_HUMAN | MMP7 | MPSL1 | PUMP1 | Matrix metalloproteinase-7 (MMP7)
Type:
Enzyme
Mol. Mass.:
29681.54
Organism:
Human
Description:
P09237
Residue:
267
Sequence:
MRLTVLCAVCLLPGSLALPLPQEAGGMSELQWEQAQDYLKRFYLYDSETKNANSLEAKLKEMQKFFGLPITGMLNSRVIEIMQKPRCGVPDVAEYSLFPNSPKWTSKVVTYRIVSYTRDLPHITVDRLVSKALNMWGKEIPLHFRKVVWGTADIMIGFARGAHGDSYPFDGPGNTLAHAFAPGTGLGGDAHFDEDERWTDGSSLGINFLYAATHELGHSLGMGHSSDPNAVMYPTYGNGDPQNFKLSQDDIKGIQKLYGKRSNSRKK
  
Inhibitor
Name:
BDBM50102482
Synonyms:
4-[carboxy-(4'-methoxy-biphenyl-4-sulfonylamino)-methyl]-piperidine-1-carboxylic acid ethyl ester | CHEMBL83955
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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