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Target
P2Y purinoceptor 4
Ligand
BDBM50306712
Substrate
n/a
Meas. Tech.
ChEMBL_147872 (CHEMBL756883)
EC50
85.0±n/a nM
Citation
 Kim, HS; Ravi, RG; Marquez, VE; Maddileti, S; Wihlborg, AK; Erlinge, D; Malmsjö, M; Boyer, JL; Harden, TK; Jacobson, KA Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors. J Med Chem 45:208-18 (2001) [PubMed]  Article 
Target
Name:
P2Y purinoceptor 4
Synonyms:
P2P | P2Y purinoceptor 4 | P2Y4 | UNR | Uridine nucleotide receptor | P2RY4_HUMAN | P2RY4 | NRU | Pyrimidinergic receptor P2Y4
Type:
PROTEIN
Mol. Mass.:
40977.17
Organism:
Human
Description:
ChEMBL_751027
Residue:
365
Sequence:
MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL
  
Inhibitor
Name:
BDBM50306712
Synonyms:
((1R,2R,3S,4R,5S)-4-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2,3-dihydroxybicyclo[3.1.0]hexan-1-yl)methyl tetrahydrogen triphosphate | CHEMBL606210
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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