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Target
Corticotropin-releasing factor receptor 2
Ligand
BDBM50026982
Substrate
n/a
Meas. Tech.
ChEMBL_51278 (CHEMBL664980)
IC50
0.920000±n/a nM
Citation
 Rivier, J; Gulyas, J; Kirby, D; Low, W; Perrin, MH; Kunitake, K; DiGruccio, M; Vaughan, J; Reubi, JC; Waser, B; Koerber, SC; Martinez, V; Wang, L; Taché, Y; Vale, W Potent and long-acting corticotropin releasing factor (CRF) receptor 2 selective peptide competitive antagonists. J Med Chem 45:4737-47 (2002) [PubMed]  Article 
Target
Name:
Corticotropin-releasing factor receptor 2
Synonyms:
CRF-R 2 | CRF2 | CRF2R | CRFR2_HUMAN | CRH-R 2 | CRH2R | CRHR2 | Corticotropin releasing factor receptor 2 | Corticotropin-releasing factor receptor 2 (CRF-2) | Corticotropin-releasing factor receptor 2/Corticotropin-releasing factor-binding protein | Corticotropin-releasing hormone receptor 2
Type:
Enzyme
Mol. Mass.:
47694.70
Organism:
Homo sapiens (Human)
Description:
Q13324
Residue:
411
Sequence:
MDAALLHSLLEANCSLALAEELLLDGWGPPLDPEGPYSYCNTTLDQIGTCWPRSAAGALVERPCPEYFNGVKYNTTRNAYRECLENGTWASKINYSQCEPILDDKQRKYDLHYRIALVVNYLGHCVSVAALVAAFLLFLALRSIRCLRNVIHWNLITTFILRNVMWFLLQLVDHEVHESNEVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTERLRKCLFLFIGWCIPFPIIVAWAIGKLYYENEQCWFGKEPGDLVDYIYQGPIILVLLINFVFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIMFIYFNSFLQSFQGFFVSVFYCFFNGEVRSAVRKRWHRWQDHHSLRVPMARAMSIPTSPTRISFHSIKQTAAV
  
Inhibitor
Name:
BDBM50026982
Synonyms:
CHEMBL2370927
Type:
Small organic molecule
Emp. Form.:
C183H307N47O56
Mol. Mass.:
4061.677
SMILES:
n/a
Structure:
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