Reaction Details Report a problem with these data
Target
Melanocortin receptor 5
Ligand
BDBM50122067
Substrate
n/a
Meas. Tech.
ChEMBL_104262 (CHEMBL711699)
EC50
750±n/a nM
Citation
 Holder, JR; Xiang, Z; Bauzo, RM; Haskell-Luevano, C Structure-activity relationships of the melanocortin tetrapeptide Ac-His-D-Phe-Arg-Trp-NH2 at the mouse melanocortin receptors. 4. Modifications at the Trp position. J Med Chem 45:5736-44 (2002) [PubMed]  Article 
Target
Name:
Melanocortin receptor 5
Synonyms:
MC5R_MOUSE | Mc5r | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R)
Type:
Enzyme
Mol. Mass.:
36966.58
Organism:
Mus musculus (Mouse)
Description:
P41149
Residue:
325
Sequence:
MNSSSTLTVLNLTLNASEDGILGSNVKNKSLACEEMGIAVEVFLTLGLVSLLENILVIGAIVKNKNLHSPMYFFVGSLAVADMLVSMSNAWETVTIYLLNNKHLVIADTFVRHIDNVFDSMICISVVASMCSLLAIAVDRYITIFYALRYHHIMTARRSGVIIACIWTFCISCGIVFIIYYESKYVIICLISMFFTMLFFMVSLYIHMFLLARNHVKRIAASPRYNSVRQRTSMKGAITLTMLLGIFIVCWSPFFLHLILMISCPQNVYCSCFMSYFNMYLILIMCNSVIDPLIYALRSQEMRRTFKEIVCCHGFRRPCRLLGGY
  
Inhibitor
Name:
BDBM50122067
Synonyms:
Ac-His-D-Phe-Arg-D-Nal(1')-NH2 | CHEMBL346925
Type:
Small organic molecule
Emp. Form.:
C36H44N10O5
Mol. Mass.:
696.7986
SMILES:
CC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1cccc2ccccc12)C(N)=O
Structure:
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