Target
D(3) dopamine receptor
Ligand
BDBM50050467
Substrate
n/a
Meas. Tech.
ChEMBL_62280 (CHEMBL675050)
Ki
60±n/a nM
Citation
 Varady, JWu, XFang, XMin, JHu, ZLevant, BWang, S Molecular modeling of the three-dimensional structure of dopamine 3 (D3) subtype receptor: discovery of novel and potent D3 ligands through a hybrid pharmacophore- and structure-based database searching approach. J Med Chem 46:4377-92 (2003) [PubMed]  Article 
Target
Name:
D(3) dopamine receptor
Synonyms:
DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3
Type:
n/a
Mol. Mass.:
44243.43
Organism:
Human
Description:
n/a
Residue:
400
Sequence:
MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERALQTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILNLCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTVCSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQQTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRKLSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHVSPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
  
Inhibitor
Name:
BDBM50050467
Synonyms:
1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol | 3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole | 4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol | CHEMBL445102 | L-741626 | L741,626
Type:
Small organic molecule
Emp. Form.:
C20H21ClN2O
Mol. Mass.:
340.847
SMILES:
OC1(CCN(Cc2c[nH]c3ccccc23)CC1)c1ccc(Cl)cc1
Structure:
Search PDB for entries with ligand similarity: