Reaction Details Report a problem with these data
Target
Motilin receptor
Ligand
BDBM50199360
Substrate
n/a
Meas. Tech.
ChEMBL_411464 (CHEMBL853861)
Ki
1197±n/a nM
Citation
 Marsault, E; Hoveyda, HR; Peterson, ML; Saint-Louis, C; Landry, A; Vézina, M; Ouellet, L; Wang, Z; Ramaseshan, M; Beaubien, S; Benakli, K; Beauchemin, S; Déziel, R; Peeters, T; Fraser, GL Discovery of a new class of macrocyclic antagonists to the human motilin receptor. J Med Chem 49:7190-7 (2006) [PubMed]  Article 
Target
Name:
Motilin receptor
Synonyms:
G-protein coupled receptor 38 | GPR38 | MLNR | MTLR | MTLR1 | MTLR_HUMAN
Type:
PROTEIN
Mol. Mass.:
45365.95
Organism:
Homo sapiens (Human)
Description:
ChEMBL_122664
Residue:
412
Sequence:
MGSPWNGSDGPEGAREPPWPALPPCDERRCSPFPLGALVPVTAVCLCLFVVGVSGNVVTVMLIGRYRDMRTTTNLYLGSMAVSDLLILLGLPFDLYRLWRSRPWVFGPLLCRLSLYVGEGCTYATLLHMTALSVERYLAICRPLRARVLVTRRRVRALIAVLWAVALLSAGPFLFLVGVEQDPGISVVPGLNGTARIASSPLASSPPLWLSRAPPPSPPSGPETAEAAALFSRECRPSPAQLGALRVMLWVTTAYFFLPFLCLSILYGLIGRELWSSRRPLRGPAASGRERGHRQTVRVLLVVVLAFIICWLPFHVGRIIYINTEDSRMMYFSQYFNIVALQLFYLSASINPILYNLISKKYRAAAFKLLLARKSRPRGFHRSRDTAGEVAGDTGGDTVGYTETSANVKTMG
  
Inhibitor
Name:
BDBM50199360
Synonyms:
(3S,6R,9R)-9-(4-hydroxy-benzyl)-6-isopropyl-3-propyl-1,4,7,10tetraaza-cyclooctadecane-2,5,8-trione | CHEMBL214869
Type:
Small organic molecule
Emp. Form.:
C27H44N4O4
Mol. Mass.:
488.6627
SMILES:
CCC[C@@H]1NC(=O)[C@H](NC(=O)[C@@H](Cc2ccc(O)cc2)NCCCCCCCCNC1=O)C(C)C
Structure:
Search PDB for entries with ligand similarity: