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Target
Sex hormone-binding globulin
Ligand
BDBM50200092
Substrate
n/a
Meas. Tech.
ChEMBL_422532 (CHEMBL911029)
IC50
10350±n/a nM
Citation
 Cherkasov, A; Ban, F; Li, Y; Fallahi, M; Hammond, GL Progressive docking: a hybrid QSAR/docking approach for accelerating in silico high throughput screening. J Med Chem 49:7466-78 (2006) [PubMed]  Article 
Target
Name:
Sex hormone-binding globulin
Synonyms:
SHBG | SHBG_HUMAN | Testis-specific androgen-binding protein
Type:
PROTEIN
Mol. Mass.:
43780.19
Organism:
Homo sapiens (Human)
Description:
ChEMBL_466706
Residue:
402
Sequence:
MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPASNLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDIPQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPLVLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTSFCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH
  
Inhibitor
Name:
BDBM50200092
Synonyms:
4-(4-(3-fluoro-4-hydroxyphenyl)hexan-3-yl)benzene-1,2-diol | CHEMBL216660 | NSC-32082
Type:
Small organic molecule
Emp. Form.:
C18H21FO3
Mol. Mass.:
304.3559
SMILES:
CCC(C(CC)c1ccc(O)c(F)c1)c1ccc(O)c(O)c1
Structure:
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