Reaction Details Report a problem with these data
Target
Amine oxidase [flavin-containing] A
Ligand
BDBM50217272
Substrate
n/a
Meas. Tech.
ChEMBL_440608
IC50
>150000±n/a nM
Citation
 Hwang, JH; Hong, SS; Han, XH; Hwang, JS; Lee, D; Lee, H; Yun, YP; Kim, Y; Ro, JS; Hwang, BY Prenylated xanthones from the root bark of Cudrania tricuspidata. J Nat Prod 70:1207-9 (2007) [PubMed]  Article  BDB Entry
Target
Name:
Amine oxidase [flavin-containing] A
Synonyms:
Amine oxidase [flavin-containing] A | MAO-A | Monoamine oxidase | Monoamine oxidase A | Monoamine oxidase type A
Type:
PROTEIN
Mol. Mass.:
59608.24
Organism:
Mus musculus
Description:
ChEMBL_122776
Residue:
526
Sequence:
MTDLEKPSITGHMFDVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQNRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDDMGKEIPVDAPWQARHAEEWDKITMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWFLWYVRQCGGTSRIFSVTNGGQERKFVGGSGQISEQIMVLLGDKVKLSSPVTYIDQTDDNIIIETLNHEHYECKYVISAIPPVLTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAFWKKKDYCGCMIIEDEEAPISITLDDTKPDGSMPAIMGFILARKAERLAKLHKDIRKRKICELYAKVLGSQEALSPVHYEEKNWCEEQYSGGCYTAYFPPGIMTLYGRVIRQPVGRIYFAGTETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVQEPESKDVPALEITHTFLERNLPSVPGLLKITGFSTSVALLCFVLYKFKQPQS
  
Inhibitor
Name:
BDBM50217272
Synonyms:
1,6,7-trihydroxy-8-(3-methylbut-2-enyl)-4',5'-dihydro-4',4',5'-trimethylfurano-(3,4:2',3')-xanthone | CHEMBL395246
Type:
Small organic molecule
Emp. Form.:
C23H24O6
Mol. Mass.:
396.4331
SMILES:
[#6]-[#6]1-[#8]-c2cc(-[#8])c3c(oc4cc(-[#8])c(-[#8])c(-[#6]\[#6]=[#6](\[#6])-[#6])c4c3=O)c2C1([#6])[#6]
Structure:
Search PDB for entries with ligand similarity: