Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50177309
Substrate
n/a
Meas. Tech.
ChEMBL_465782 (CHEMBL931051)
Ki
321±n/a nM
Citation
 Jeong, LS; Lee, HW; Kim, HO; Tosh, DK; Pal, S; Choi, WJ; Gao, ZG; Patel, AR; Williams, W; Jacobson, KA; Kim, HD Structure-activity relationships of 2-chloro-N6-substituted-4'-thioadenosine-5'-N,N-dialkyluronamides as human A3 adenosine receptor antagonists. Bioorg Med Chem Lett 18:1612-6 (2008) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
Adenosine A3 receptor | AA3R_RAT | Adora3 | Adenosine receptor A2a and A3
Type:
PROTEIN
Mol. Mass.:
36643.73
Organism:
Rat
Description:
ChEMBL_479910
Residue:
320
Sequence:
MKANNTTTSALWLQITYITMEAAIGLCAVVGNMLVIWVVKLNRTLRTTTFYFIVSLALADIAVGVLVIPLAIAVSLEVQMHFYACLFMSCVLLVFTHASIMSLLAIAVDRYLRVKLTVRYRTVTTQRRIWLFLGLCWLVSFLVGLTPMFGWNRKVTLELSQNSSTLSCHFRSVVGLDYMVFFSFITWILIPLVVMCIIYLDIFYIIRNKLSQNLTGFRETRAFYGREFKTAKSLFLVLFLFALCWLPLSIINFVSYFNVKIPEIAMCLGILLSHANSMMNPIVYACKIKKFKETYFVILRACRLCQTSDSLDSNLEQTTE
  
Inhibitor
Name:
BDBM50177309
Synonyms:
(2S,3S,4R,5R)-5-(6-(3-iodobenzylamino)-2-chloro-9H-purin-9-yl)-3,4-dihydroxy-N,N-dimethyl-tetrahydrothiophene-2-carboxamide | (2S,3S,4R,5R)-5-[2-chloro-6-(3-iodo-benzylamino)-purin-9-yl]-3,4-dihydroxy-tetrahydro-thiophene-2-carboxylic aciddimethylamide | CHEMBL436485
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: