Reaction Details Report a problem with these data
Target
Melanocortin receptor 5
Ligand
BDBM50373479
Substrate
n/a
Meas. Tech.
ChEMBL_467904 (CHEMBL925938)
EC50
1600±n/a nM
Citation
Guo, L; Ye, Z; Ujjainwalla, F; Sings, HL; Sebhat, IK; Huber, J; Weinberg, DH; Tang, R; MacNeil, T; Tamvakopoulos, C; Peng, Q; MacIntyre, E; van der Ploeg, LH; Goulet, MT; Wyvratt, MJ; Nargund, RP Synthesis and SAR of potent and orally bioavailable tert-butylpyrrolidine archetype derived melanocortin subtype-4 receptor modulators. Bioorg Med Chem Lett 18:3242-7 (2008) [PubMed] Article
More Info.:
Target
Name:
Melanocortin receptor 5
Synonyms:
MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R)
Type:
Enzyme
Mol. Mass.:
36612.92
Organism:
Homo sapiens (Human)
Description:
P33032
Residue:
325
Sequence:
MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD