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Target
Adenosine receptor A2b
Ligand
BDBM21220
Substrate
n/a
Meas. Tech.
ChEMBL_478884 (CHEMBL937355)
EC50
7144963±n/a nM
Citation
 Ivanov, AA; Wang, B; Klutz, AM; Chen, VL; Gao, ZG; Jacobson, KA Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists. J Med Chem 51:2088-99 (2008) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
ADENOSINE A2B | Adenosine receptor A2B (A2B) | AA2BR_HUMAN | ADORA2B | Adenosine receptors; A2a & A2b | Adenosine receptors A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Human
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM21220
Synonyms:
CHEMBL464859 | N-Ethylcarboxamidoadenosine | Adenosine-5-(N-ethylcarboxamide) | (2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,4-dihydroxyoxolane-2-carboxamide | Adenosine, N6-Ethyl-carboxamido | Adenosine analog, 3 | NECA
Type:
Antineoplastic Agent
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: