Reaction Details Report a problem with these data
Target
Adenosine receptor A2b
Ligand
BDBM50202575
Substrate
n/a
Meas. Tech.
ChEMBL_478884 (CHEMBL937355)
EC50
1659587±n/a nM
Citation
 Ivanov, AA; Wang, B; Klutz, AM; Chen, VL; Gao, ZG; Jacobson, KA Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists. J Med Chem 51:2088-99 (2008) [PubMed]  Article 
Target
Name:
Adenosine receptor A2b
Synonyms:
ADENOSINE A2B | Adenosine receptor A2B (A2B) | AA2BR_HUMAN | ADORA2B | Adenosine receptors; A2a & A2b | Adenosine receptors A2b
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36341.22
Organism:
Human
Description:
n/a
Residue:
332
Sequence:
MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAIPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYTFHKIISRYLLCQADVKSGNGQAGVQPALGVGL
  
Inhibitor
Name:
BDBM50202575
Synonyms:
1-deoxy-1-{2-chloro-6-[N'-(2-thiophen-2-yl-acetyl)-hydrazino]-9H-purin-9-yl}-N-ethyl-beta-D-ribofuranuronamide | N'-(2-chloro-9-((2R,3R,4S,5S)-5-(ethylcarbamoyl)-3,4-dihydroxy-tetrahydrofuran-2-yl)-9H-purin-6-yl)-2-(thiophen-2-yl)acetohydrazide | CHEMBL217952
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: