Target
Aspartate-semialdehyde dehydrogenase
Ligand
BDBM50269414
Substrate
n/a
Meas. Tech.
ChEMBL_550047 (CHEMBL662416)
IC50
180±n/a nM
Citation
 Carroll, ARNgo, AQuinn, RJRedburn, JHooper, JN Petrosamine B, an inhibitor of the Helicobacter pylori enzyme aspartyl semialdehyde dehydrogenase from the Australian sponge Oceanapia sp. J Nat Prod 68:804-6 (2005) [PubMed]  Article  BDB Entry
Target
Name:
Aspartate-semialdehyde dehydrogenase
Synonyms:
n/a
Type:
PROTEIN
Mol. Mass.:
38120.98
Organism:
Helicobacter pylori
Description:
ChEMBL_550047
Residue:
346
Sequence:
MKTYNVAIVGASGAVGQELIKGLENSFFPIKKFVPLASTRSAGKKIKAFNKDYEILETTHEVFEREKIDIAFFSAGGSVSEEFATSASKTALVVDNTSFFRLNKDVPLVVPEINAKEIFNAPLNIIANPNCSTIQMTQILNPLHLHFKIKSVIVSTYQAVSGAGNKGIESLKNELKTALECLEKDPTIDLNQVLQAGAFAYPIAFNAIAHIDTFKENGYTKEELKMLHETHKIMGVDFPISATCVRVPVLRSHSESLSIAFEKEFDLKEVYEVLKNAPSVAVCDDPSHNLYPTPLKASHTDSVFIGRLRKDLFDKKTLHGFCVADQLRVGAATNALKIALHYIKNA
  
Inhibitor
Name:
BDBM50269414
Synonyms:
CHEMBL457665 | CYSTEINE-S-SULFONIC ACID | S-sulpho-L-cysteine
Type:
Small organic molecule
Emp. Form.:
C3H7NO5S2
Mol. Mass.:
201.221
SMILES:
N[C@@H](CSS(O)(=O)=O)C(O)=O |r|
Structure:
Search PDB for entries with ligand similarity: