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Target
Prostaglandin G/H synthase 1
Ligand
BDBM22360
Substrate
n/a
Meas. Tech.
ChEMBL_547440 (CHEMBL1029255)
IC50
1000000±n/a nM
Citation
 Noreen, Y; el-Seedi, H; Perera, P; Bohlin, L Two new isoflavones from Ceiba pentandra and their effect on cyclooxygenase-catalyzed prostaglandin biosynthesis. J Nat Prod 61:8-12 (1998) [PubMed]  Article 
Target
Name:
Prostaglandin G/H synthase 1
Synonyms:
Cyclooxygenase-1 | PGH1_BOVIN | PTGS1 | COX-1 | COX1 | Cyclooxygenase
Type:
PROTEIN
Mol. Mass.:
68814.10
Organism:
Bovine
Description:
ChEMBL_547440
Residue:
600
Sequence:
MSRQGISLRFPLLLLLLSPSPVLPADPGAPAPVNPCCYYPCQHQGICVRFGLDRYQCDCTRTGYYGPNCTIPEIWTWLRTTLRPSPSFVHFLLTHGRWLWDFVNATFIRDKLMRLVLTVRSNLIPSPPTYNVAHDYISWESFSNVSYYTRILPSVPRDCPTPMGTKGKKQLPDAEFLSRRFLLRRKFIPDPQGTNLMFAFFAQHFTHQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQMLNGEVYPPSVEEAPVLMHYPRGIPPQSQMAVGQEVFGLLPGLMVYATIWLREHNRVCDLLKAEHPTWGDEQLFQTARLILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGAQFQYRNRIAMEFNQLYHWHPLMPDSFRVGPQDYSYEQFLFNTSMLVDYGVEALVDAFSRQPAGRIGGGRNIDHHILHVAVDVIKESRELRLQPFNEYRKRFGMKPYTSFQELTGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMIEMGAPFSLKGLLGNPICSPEYWKASTFGGDVGFNLVKTATLKKLVCLNTKTCPYVSFHVPDPHREDRPGVERPPTEL
  
Inhibitor
Name:
BDBM22360
Synonyms:
2-(acetyloxy)benzoic acid | 2-(acetyloxy)benzoate | Polopirin | cid_2244 | Zorprin | Acetylsalicylic acid | acetylsalicylate | Endosprin | Aspirin
Type:
Anti-Inflammatory Agents, Non-Steroidal
Emp. Form.:
C9H8O4
Mol. Mass.:
180.04
SMILES:
CC(=O)Oc1ccccc1C(=O)O
Structure:
Search PDB for entries with ligand similarity: