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Target
Carbonic anhydrase 5A, mitochondrial
Ligand
BDBM10888
Substrate
n/a
Meas. Tech.
ChEMBL_592887 (CHEMBL1046632)
Ki
20±n/a nM
Citation
 Temperini, C; Innocenti, A; Scozzafava, A; Parkkila, S; Supuran, CT The coumarin-binding site in carbonic anhydrase accommodates structurally diverse inhibitors: the antiepileptic lacosamide as an example and lead molecule for novel classes of carbonic anhydrase inhibitors. J Med Chem 53:850-4 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 5A, mitochondrial
Synonyms:
CA-VA | Carbonic anhydrase 5A (CA VA) | Carbonic anhydrase 5A, mitochondrial | Carbonic anhydrase VA (CA VA) | Carbonate dehydratase VA | Carbonic anhydrase 5A, mitochondrial precursor | CAH5A_HUMAN | CA5A | CA5 | Carbonic anhydrase V | Carbonic Anhydrase VA
Type:
Enzyme
Mol. Mass.:
34755.54
Organism:
Human
Description:
Human (cloned) isozyme
Residue:
305
Sequence:
MLGRNTWKTSAFSFLVEQMWAPLWSRSMRPGRWCSQRSCAWQTSNNTLHPLWTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSYEAASCLYIWNTGYLFQVEFDDATEASGISGGPLENHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNYKEAVVGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLLPTCWDYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEEEKMMVNNYRPLQPLMNRKVWASFQATNEGTRS
  
Inhibitor
Name:
BDBM10888
Synonyms:
Zonisamide, 1 | 1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 | Zonisamide, ZNS | SPR_2 | Zonisamide (ZNS) | Zonisamide | Zonisamide (ZNA) | US10172837, Zonisamide
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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