Reaction Details Report a problem with these data
Target
Galanin receptor type 1
Ligand
BDBM50273370
Substrate
n/a
Meas. Tech.
ChEMBL_610344 (CHEMBL1072076)
Ki
0.010000±n/a nM
Citation
 Robertson, CR; Scholl, EA; Pruess, TH; Green, BR; White, HS; Bulaj, G Engineering galanin analogues that discriminate between GalR1 and GalR2 receptor subtypes and exhibit anticonvulsant activity following systemic delivery. J Med Chem 53:1871-5 (2010) [PubMed]  Article 
Target
Name:
Galanin receptor type 1
Synonyms:
Galanin receptor 1 | Galanin receptor type 1 | GAL1-R | Galanin R1 | GALR1_HUMAN | GALR1 | GALNR | GALNR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38976.60
Organism:
Human
Description:
Galanin R1 GALR1 HUMAN::P47211
Residue:
349
Sequence:
MELAVGNLSEGNASWPEPPAPEPGPLFGIGVENFVTLVVFGLIFALGVLGNSLVITVLARSKPGKPRSTTNLFILNLSIADLAYLLFCIPFQATVYALPTWVLGAFICKFIHYFFTVSMLVSIFTLAAMSVDRYVAIVHSRRSSSLRVSRNALLGVGCIWALSIAMASPVAYHQGLFHPRASNQTFCWEQWPDPRHKKAYVVCTFVFGYLLPLLLICFCYAKVLNHLHKKLKNMSKKSEASKKKTAQTVLVVVVVFGISWLPHHIIHLWAEFGVFPLTPASFLFRITAHCLAYSNSSVNPIIYAFLSENFRKAYKQVFKCHIRKDSHLSDTKESKSRIDTPPSTNCTHV
  
Inhibitor
Name:
BDBM50273370
Synonyms:
CHEMBL503473 | M35 | Galanin (1-13)-bradikinin(2-9) | Galanin-(1-13)-bradykinin-(2-9)-amide | GWTLNSAGYLLGPPPGFSPFR-CONH2
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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