Reaction Details Report a problem with these data
Target
Type-2 angiotensin II receptor
Ligand
BDBM50321070
Substrate
n/a
Meas. Tech.
ChEMBL_637186 (CHEMBL1167160)
Ki
2.3±n/a nM
Citation
 Mahalingam, AK; Wan, Y; Murugaiah, AM; Wallinder, C; Wu, X; Plouffe, B; Botros, M; Nyberg, F; Hallberg, A; Gallo-Payet, N; Alterman, M Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition. Bioorg Med Chem 18:4570-90 (2010) [PubMed]  Article 
Target
Name:
Type-2 angiotensin II receptor
Synonyms:
Angiotensin type II receptor
Type:
PROTEIN
Mol. Mass.:
15474.49
Organism:
Sus scrofa
Description:
ChEMBL_1285617
Residue:
137
Sequence:
MAFPPEKYAQWSAGIALMKNILGFIIPLVFIATCYFGIRKHLLKTNSYGKNRITRDQVLNMAAAVVLAFIICWLPFHVLTFLDALAWMGIINSCEVIAVIDLALPFAILLGFTNSCINPFLYCFVGNRFQQKLRSVF
  
Inhibitor
Name:
BDBM50321070
Synonyms:
CHEMBL1164560 | N-Butyloxycarbonyl-3-(4-pyrazole-1-yl-methylphenyl)-5-iso-butylthiophene-2-sulfonamide
Type:
Small organic molecule
Emp. Form.:
C23H29N3O4S2
Mol. Mass.:
475.624
SMILES:
CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2cccn2)cc1
Structure:
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