Reaction Details Report a problem with these data
Target
Carbonic anhydrase 14
Ligand
BDBM23926
Substrate
n/a
Meas. Tech.
ChEMBL_651954 (CHEMBL1227627)
Ki
830±n/a nM
Citation
 Innocenti, A; Gülçin, I; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Antioxidant polyphenols effectively inhibit mammalian isoforms I-XV. Bioorg Med Chem Lett 20:5050-3 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 14
Synonyms:
Carbonate dehydratase XIV | Carbonic anhydrase 14 | CA-XIV | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV) | CAH14_HUMAN | CA14 | Carbonic anhydrase | Carbonic Anhydrase XIV
Type:
Enzyme
Mol. Mass.:
37665.67
Organism:
Human
Description:
Human (cloned) isozyme.
Residue:
337
Sequence:
MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDLPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGGSEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQLEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVGCLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
  
Inhibitor
Name:
BDBM23926
Synonyms:
5-[(E)-2-(4-hydroxyphenyl)ethenyl]benzene-1,3-diol | cid_445154 | (E)-resveratrol | Resveratol | CHEMBL165 | Stilbene, 2f | trans-resveratrol | resveratrol | US11866416, Example 7 | US20240398793, Compound 1
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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