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Target
P2Y purinoceptor 4
Ligand
BDBM50336787
Substrate
n/a
Meas. Tech.
ChEMBL_718669 (CHEMBL634425)
IC50
>10000±n/a nM
Citation
 Baqi, Y; Hausmann, R; Rosefort, C; Rettinger, J; Schmalzing, G; Müller, CE Discovery of potent competitive antagonists and positive modulators of the P2X2 receptor. J Med Chem 54:817-30 (2012) [PubMed]  Article  BDB Entry
Target
Name:
P2Y purinoceptor 4
Synonyms:
P2P | P2Y purinoceptor 4 | P2Y4 | Pyrimidinergic receptor P2Y4 | UNR | Uridine nucleotide receptor
Type:
PROTEIN
Mol. Mass.:
40977.17
Organism:
Homo sapiens (Human)
Description:
ChEMBL_751027
Residue:
365
Sequence:
MASTESSLLRSLGLSPGPGSSEVELDCWFDEDFKFILLPVSYAVVFVLGLGLNAPTLWLFIFRLRPWDATATYMFHLALSDTLYVLSLPTLIYYYAAHNHWPFGTEICKFVRFLFYWNLYCSVLFLTCISVHRYLGICHPLRALRWGRPRLAGLLCLAVWLVVAGCLVPNLFFVTTSNKGTTVLCHDTTRPEEFDHYVHFSSAVMGLLFGVPCLVTLVCYGLMARRLYQPLPGSAQSSSRLRSLRTIAVVLTVFAVCFVPFHITRTIYYLARLLEADCRVLNIVNVVYKVTRPLASANSCLDPVLYLLTGDKYRRQLRQLCGGGKPQPRTAASSLALVSLPEDSSCRWAATPQDSSCSTPRADRL
  
Inhibitor
Name:
BDBM50336787
Synonyms:
CHEMBL445413 | sodium 1-amino-9,10-dioxo-4-(m-tolylamino)-9,10-dihydroanthracene-2-sulfonate | sodium 4-(m-toluidino)-1-amino-9,10-dioxo-9,10-dihydroanthracene-2-sulfonate
Type:
Small organic molecule
Emp. Form.:
C21H15N2O5S
Mol. Mass.:
407.42
SMILES:
Cc1cccc(Nc2cc(c(N)c3C(=O)c4ccccc4C(=O)c23)S([O-])(=O)=O)c1
Structure:
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