Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 3A
Ligand
BDBM50379005
Substrate
n/a
Meas. Tech.
ChEMBL_809641 (CHEMBL2015860)
Ki
7.7±n/a nM
Citation
 Cappelli, A; Manini, M; Paolino, M; Gallelli, A; Anzini, M; Mennuni, L; Del Cadia, M; De Rienzo, F; Menziani, MC; Vomero, S Bivalent Ligands for the Serotonin 5-HT3 Receptor. ACS Med Chem Lett 2:571-576 (2011) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 3A
Synonyms:
Zacopride site-R | 5-hydroxytryptamine receptor 3A | 5-HT3 | 5HT3A_RAT | Htr3a | 5ht3 | Htr3 | Serotonin (5-HT) receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
55428.70
Organism:
Rat
Description:
5-HT3 HTR3A RAT::P35563
Residue:
483
Sequence:
MPLCIPQVLLALFLSVLIAQGEGSRRRATQAHSTTQPALLRLSDHLLANYKKGVRPVRDWRKPTLVSIDVIMYAILNVDEKNQVLTTYIWYRQFWTDEFLQWTPEDFDNVTKLSIPTDSIWVPDILINEFVDVGKSPSIPYVYVHHQGEVQNYKPLQLVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINISLWRTPEEVRSDKSIFINQGEWELLGVFTKFQEFSIETSNSYAEMKFYVVIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDSGERVSFKITLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVQLVHKQDLQRPVPDWLRHLVLDRIAWLLCLGEQPMAHRPPATFQANKTDDCSAMGNHCSHVGSPQDLEKTSRSRDSPLPPPREASLAVRGLLQELSSIRHSLEKRDEMREVARDWLRVGYVLDRLLFRIYLLAVLAYSITLVTLWSIWHYS
  
Inhibitor
Name:
BDBM50379005
Synonyms:
CHEMBL2011586
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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