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Target
Lysosomal Pro-X carboxypeptidase
Ligand
BDBM50382913
Substrate
n/a
Meas. Tech.
ChEMBL_815280 (CHEMBL2026495)
IC50
0.3±n/a nM
Citation
 Graham, TH; Liu, W; Verras, A; Sebhat, IK; Xiong, Y; Bleasby, K; Bhatt, UR; Chen, Q; Garcia-Calvo, M; Geissler, WM; Gorski, JN; He, H; Lassman, ME; Lisnock, J; Li, X; Shen, Z; Tong, X; Tung, EC; Wiltsie, J; Xiao, J; Xie, D; Xu, S; Hale, JJ; Pinto, S; Shen, DM A new class of prolylcarboxypeptidase inhibitors, part 1: discovery and evaluation. Bioorg Med Chem Lett 22:2811-7 (2012) [PubMed]  Article 
Target
Name:
Lysosomal Pro-X carboxypeptidase
Synonyms:
Proline carboxypeptidase | Prolylcarboxypeptidase | PCP_MOUSE | Prcp
Type:
PROTEIN
Mol. Mass.:
55028.96
Organism:
Mouse
Description:
ChEMBL_1335505
Residue:
491
Sequence:
MGCRALLLLSFLLLGAATTIPPRLKTLGSPHLSASPTPDPAVARKYSVLYFEQKVDHFGFADMRTFKQRYLVADKHWQRNGGSILFYTGNEGDIVWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGQDSFKDSQHLNFLTSEQALADFAELIRHLEKTIPGAQGQPVIAIGGSYGGMLAAWFRMKYPHIVVGALAASAPIWQLDGMVPCGEFMKIVTNDFRKSGPYCSESIRKSWNVIDKLSGSGSGLQSLTNILHLCSPLTSEKIPTLKGWIAETWVNLAMVNYPYACNFLQPLPAWPIKEVCQYLKNPNVSDTVLLQNIFQALSVYYNYSGQAACLNISQTTTSSLGSMGWSFQACTEMVMPFCTNGIDDMFEPFLWDLEKYSNDCFNQWGVKPRPHWMTTMYGGKNISSHSNIIFSNGELDPWSGGGVTRDITDTLVAINIHDGAHHLDLRAHNAFDPSSVLLSRLLEVKHMKKWILDFYSNIQ
  
Inhibitor
Name:
BDBM50382913
Synonyms:
CHEMBL2023210
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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