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Target
Cannabinoid receptor 2
Ligand
BDBM50395176
Substrate
n/a
Meas. Tech.
ChEMBL_859792 (CHEMBL2169620)
Ki
3.45±n/a nM
Citation
 Baraldi, PG; Saponaro, G; Moorman, AR; Romagnoli, R; Preti, D; Baraldi, S; Ruggiero, E; Varani, K; Targa, M; Vincenzi, F; Borea, PA; Aghazadeh Tabrizi, M 7-Oxo-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxamides as selective CB(2) cannabinoid receptor ligands: structural investigations around a novel class of full agonists. J Med Chem 55:6608-23 (2012) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
39690.94
Organism:
Homo sapiens (Human)
Description:
P34972
Residue:
360
Sequence:
MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCSELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLDVRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
  
Inhibitor
Name:
BDBM50395176
Synonyms:
CHEMBL2163952
Type:
Small organic molecule
Emp. Form.:
C30H32N2O3
Mol. Mass.:
468.5867
SMILES:
CC12CC3CC(C)(C1)CC(C3)(C2)NC(=O)c1cn2C(COc3cccc(c23)c1=O)c1ccccc1 |TLB:6:5:11:2.3.10,4:5:11:2.3.10,4:3:7.5.8:11,12:9:7:2.4.3,10:9:7:2.4.3,THB:10:3:7:8.9.11|
Structure:
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