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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50400116
Substrate
n/a
Meas. Tech.
ChEMBL_878114 (CHEMBL2183304)
Ki
557±n/a nM
Citation
 Abdelhafez, OM; Amin, KM; Ali, HI; Abdalla, MM; Batran, RZ Synthesis of new 7-oxycoumarin derivatives as potent and selective monoamine oxidase A inhibitors. J Med Chem 55:10424-36 (2012) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
Amine oxidase [flavin-containing] B | MAO-B | Monoamine oxidase B | Monoamine oxidase type B | AOFB_BOVIN | MAOB | Monoamine oxidase | Monoamine Oxidase Type B (MAO-B)
Type:
PROTEIN
Mol. Mass.:
58428.94
Organism:
Bovine
Description:
ChEMBL_1501478
Residue:
520
Sequence:
MSSKCDVVVVGGGISGMAAAKLLHDSGLNVIVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNHILRLSKELGLETYKVNEVERLIHHTKGKSYPFRGSFPSVWNPITYLDHNNLWRTMDDMGREIPSDAPWKAPLAEQWDLMTMKELLDKICWTESSKQLAILFVNLCVTAEIHEVSALWFLWYVKQCGGTTRIFSTSNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIHIDQTGENVLVETLNHELYEAKYVISAVPPVLGMKIHFNPPLPMMRNQLITRVPLGSVIKSIVYYKEPFWRNMDYCGSMIIEGEEAPVAYALDDTKPDGSYPAIIGFILAHKARKLARLTKEERLKKLCDLYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTSYFPPGIMTQYGRVLRQPVGRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWLPEPESVDVPAKPITTTFLQRHLPSVPGLLKLIGLTTIFSATALGFLAHKRGLLVRI
  
Inhibitor
Name:
BDBM50400116
Synonyms:
CHEMBL2178435
Type:
Small organic molecule
Emp. Form.:
C21H16ClN3O5S
Mol. Mass.:
n/a
SMILES:
Cc1cc(=O)oc2cc(OCC(=O)Nn3c(O)csc3=Nc3ccc(Cl)cc3)ccc12 |w:20.21|
Structure:
Search PDB for entries with ligand similarity: