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Target
Apoptosis regulator Bcl-2
Ligand
BDBM50400179
Substrate
n/a
Meas. Tech.
ChEMBL_878600 (CHEMBL2188685)
Ki
71±n/a nM
Citation
 Zhang, Z; Li, X; Song, T; Zhao, Y; Feng, Y An anthraquinone scaffold for putative, two-face Bim BH3a-helix mimic. J Med Chem 55:10735-41 (2012) [PubMed]  Article 
Target
Name:
Apoptosis regulator Bcl-2
Synonyms:
Apoptosis regulator Bcl-2 Protein | B-cell lymphoma 2 protein (Bcl-2) | BCL-2 | BCL2 | BCL2_HUMAN | Bcl-2 Protein
Type:
Homodimer or heterodimer
Mol. Mass.:
26269.11
Organism:
Homo sapiens (Human)
Description:
P10415
Residue:
239
Sequence:
MAHAGRTGYDNREIVMKYIHYKLSQRGYEWDAGDVGAAPPGAAPAPGIFSSQPGHTPHPAASRDPVARTSPLQTPAAPGAAAGPALSPVPPVVHLTLRQAGDDFSRRYRRDFAEMSSQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREMSPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYGPSMRPLFDFSWLSLKTLLSLALVGACITLGAYLGHK
  
Inhibitor
Name:
BDBM50400179
Synonyms:
2,3‐dihydroxy‐6‐(phenylsulfanyl)anthracene‐9,10‐ dione (Ligand 4) | CHEMBL2180319
Type:
Small organic molecule
Emp. Form.:
C20H12O4S
Mol. Mass.:
348.372
SMILES:
Oc1cc2C(=O)c3ccc(Sc4ccccc4)cc3C(=O)c2cc1O
Structure:
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