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Target
C-C chemokine receptor type 1
Ligand
BDBM50401547
Substrate
n/a
Meas. Tech.
ChEMBL_882641 (CHEMBL2213078)
Ki
316.23±n/a nM
Citation
 Smethurst, CA; Bevan, N; Brooks, C; Emmons, A; Gough, PJ; Mookherjee, C; Moores, K; Peace, S; Philp, J; Piercy, V; Watson, SP; Zippoli, M In vivo activity of an azole series of CCR2 antagonists. Bioorg Med Chem Lett 22:7252-5 (2012) [PubMed]  Article 
Target
Name:
C-C chemokine receptor type 1
Synonyms:
C-C CKR-1 | C-C chemokine receptor type 1 (CCR1) | CC-CKR-1 | CCR-1 | CCR1 | CCR1_HUMAN | CD_antigen=CD191 | CMKBR1 | CMKR1 | HM145 | LD78 receptor | MIP-1alpha-R | Macrophage inflammatory protein 1-alpha receptor | RANTES-R | SCYAR1
Type:
Enzyme
Mol. Mass.:
41180.69
Organism:
Homo sapiens (Human)
Description:
P32246
Residue:
355
Sequence:
METPNTTEDYDTTTEFDYGDATPCQKVNERAFGAQLLPPLYSLVFVIGLVGNILVVLVLVQYKRLKNMTSIYLLNLAISDLLFLFTLPFWIDYKLKDDWVFGDAMCKILSGFYYTGLYSEIFFIILLTIDRYLAIVHAVFALRARTVTFGVITSIIIWALAILASMPGLYFSKTQWEFTHHTCSLHFPHESLREWKLFQALKLNLFGLVLPLLVMIICYTGIIKILLRRPNEKKSKAVRLIFVIMIIFFLFWTPYNLTILISVFQDFLFTHECEQSRHLDLAVQVTEVIAYTHCCVNPVIYAFVGERFRKYLRQLFHRRVAVHLVKWLPFLSVDRLERVSSTSPSTGEHELSAGF
  
Inhibitor
Name:
BDBM50401547
Synonyms:
CHEMBL2207098
Type:
Small organic molecule
Emp. Form.:
C15H10Cl4N4O2S
Mol. Mass.:
452.143
SMILES:
Clc1ccc(cc1Cl)S(=O)(=O)Nc1cc(Cl)c(Cl)cc1Cn1ccnn1
Structure:
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