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Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM50058283
Substrate
n/a
Meas. Tech.
ChEMBL_1399 (CHEMBL616188)
IC50
13182.57±n/a nM
Citation
 Prunier, H; Rault, S; Lancelot, JC; Robba, M; Renard, P; Delagrange, P; Pfeiffer, B; Caignard, DH; Misslin, R; Guardiola-Lemaitre, B; Hamon, M Novel and selective partial agonists of 5-HT3 receptors. 2. Synthesis and biological evaluation of piperazinopyridopyrrolopyrazines, piperazinopyrroloquinoxalines, and piperazinopyridopyrroloquinoxalines. J Med Chem 40:1808-19 (1997) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT1B | Serotonin 1 (5-HT1) receptor | Serotonin receptor 1B | 5-HT-1B | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_RAT | Htr1b | 5ht1b | Serotonin 1B/1D receptor
Type:
Protein
Mol. Mass.:
43173.33
Organism:
Rat
Description:
P28564
Residue:
386
Sequence:
MEEQGIQCAPPPPATSQTGVPLANLSHNCSADDYIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVDYSAKRTPKRAAIMIVLVWVFSISISLPPFFWRQAKAEEEVLDCFVNTDHVLYTVYSTVGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTSSVTSINSRVPEVPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMAIFDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCTG
  
Inhibitor
Name:
BDBM50058283
Synonyms:
6-(4-Benzyl-piperazin-1-yl)-pyrido[3,2-e]pyrrolo[1,2-a]pyrazine | CHEMBL53573
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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