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Target
Sex hormone-binding globulin
Ligand
BDBM50423549
Substrate
n/a
Meas. Tech.
ChEMBL_466706 (CHEMBL922711)
Kd
0.891000±n/a nM
Citation
 Cherkasov, A; Ban, F; Santos-Filho, O; Thorsteinson, N; Fallahi, M; Hammond, GL An updated steroid benchmark set and its application in the discovery of novel nanomolar ligands of sex hormone-binding globulin. J Med Chem 51:2047-56 (2008) [PubMed]  Article 
Target
Name:
Sex hormone-binding globulin
Synonyms:
SHBG | SHBG_HUMAN | Testis-specific androgen-binding protein
Type:
PROTEIN
Mol. Mass.:
43780.19
Organism:
Homo sapiens (Human)
Description:
ChEMBL_466706
Residue:
402
Sequence:
MESRGPLATSRLLLLLLLLLLRHTRQGWALRPVLPTQSAHDPPAVHLSNGPGQEPIAVMTFDLTKITKTSSSFEVRTWDPEGVIFYGDTNPKDDWFMLGLRDGRPEIQLHNHWAQLTVGAGPRLDDGRWHQVEVKMEGDSVLLEVDGEEVLRLRQVSGPLTSKRHPIMRIALGGLLFPASNLRLPLVPALDGCLRRDSWLDKQAEISASAPTSLRSCDVESNPGIFLPPGTQAEFNLRDIPQPHAEPWAFSLDLGLKQAAGSGHLLALGTPENPSWLSLHLQDQKVVLSSGSGPGLDLPLVLGLPLQLKLSMSRVVLSQGSKMKALALPPLGLAPLLNLWAKPQGRLFLGALPGEDSSTSFCLNGLWAQGQRLDVDQALNRSHEIWTHSCPQSPGNGTDASH
  
Inhibitor
Name:
BDBM50423549
Synonyms:
6Alpha-Fluoro-Dihydrotestosterone | CHEMBL408707
Type:
Small organic molecule
Emp. Form.:
C19H29FO2
Mol. Mass.:
308.4308
SMILES:
C[C@]12CC[C@H]3[C@@H](C[C@H](F)[C@H]4CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
Structure:
Search PDB for entries with ligand similarity: