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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50423568
Substrate
n/a
Meas. Tech.
ChEMBL_468124 (CHEMBL934144)
IC50
158±n/a nM
Citation
 Hall, A; Bit, RA; Brown, SH; Chowdhury, A; Giblin, GM; Hurst, DN; Kilford, IR; Lewell, X; Naylor, A; Scoccitti, T Novel methylene-linked heterocyclic EP1 receptor antagonists. Bioorg Med Chem Lett 18:1592-7 (2008) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor
Type:
Enzyme
Mol. Mass.:
41834.57
Organism:
Homo sapiens (Human)
Description:
P34995
Residue:
402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
  
Inhibitor
Name:
BDBM50423568
Synonyms:
CHEMBL403459
Type:
Small organic molecule
Emp. Form.:
C20H18ClNO3
Mol. Mass.:
355.815
SMILES:
Cc1cc(cn1Cc1cc(Cl)ccc1OCc1ccccc1)C(O)=O
Structure:
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