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Target
Peroxisome proliferator-activated receptor alpha
Ligand
BDBM28759
Substrate
n/a
Meas. Tech.
ChEMBL_934960 (CHEMBL2320329)
EC50
190±n/a nM
Citation
 Laghezza, A; Pochetti, G; Lavecchia, A; Fracchiolla, G; Faliti, S; Piemontese, L; Di Giovanni, C; Iacobazzi, V; Infantino, V; Montanari, R; Capelli, D; Tortorella, P; Loiodice, F New 2-(aryloxy)-3-phenylpropanoic acids as peroxisome proliferator-activated receptora/¿ dual agonists able to upregulate mitochondrial carnitine shuttle system gene expression. J Med Chem 56:60-72 (2013) [PubMed]  Article 
Target
Name:
Peroxisome proliferator-activated receptor alpha
Synonyms:
Peroxisome proliferator-activated receptor | PPAR-alpha | Nuclear receptor subfamily 1 group C member 1 | PPAR alpha/gamma | Peroxisome Proliferator-Activated Receptor alpha | Peroxisome proliferator-activated receptor alpha (PPAR alpha) | PPARA_HUMAN | PPARA | NR1C1 | PPAR
Type:
Enzyme
Mol. Mass.:
52222.08
Organism:
Human
Description:
Q07869
Residue:
468
Sequence:
MVDTESPLCPLSPLEAGDLESPLSEEFLQEMGNIQEISQSIGEDSSGSFGFTEYQYLGSCPGSDGSVITDTLSPASSPSSVTYPVVPGSVDESPSGALNIECRICGDKASGYHYGVHACEGCKGFFRRTIRLKLVYDKCDRSCKIQKKNRNKCQYCRFHKCLSVGMSHNAIRFGRMPRSEKAKLKAEILTCEHDIEDSETADLKSLAKRIYEAYLKNFNMNKVKARVILSGKASNNPPFVIHDMETLCMAEKTLVAKLVANGIQNKEAEVRIFHCCQCTSVETVTELTEFAKAIPGFANLDLNDQVTLLKYGVYEAIFAMLSSVMNKDGMLVAYGNGFITREFLKSLRKPFCDIMEPKFDFAMKFNALELDDSDISLFVAAIICCGDRPGLLNVGHIEKMQEGIVHVLRLHLQSNHPDDIFLFPKLLQKMADLRQLVTEHAQLVQIIKKTESDAALHPLLQEIYRDMY
  
Inhibitor
Name:
BDBM28759
Synonyms:
CHEMBL191275 | (2S)-3-phenyl-2-(4-phenylphenoxy)propanoic acid | LT175 (S-1)
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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