Reaction Details Report a problem with these data
Target
Neuronal acetylcholine receptor subunit alpha-7
Ligand
BDBM10759
Substrate
n/a
Meas. Tech.
ChEMBL_936603 (CHEMBL2318766)
Ki
170000±n/a nM
Citation
 Ussing, CA; Hansen, CP; Petersen, JG; Jensen, AA; Rohde, LA; Ahring, PK; Nielsen, EØ; Kastrup, JS; Gajhede, M; Frølund, B; Balle, T Synthesis, pharmacology, and biostructural characterization of novela4ß2 nicotinic acetylcholine receptor agonists. J Med Chem 56:940-51 (2013) [PubMed]  Article 
Target
Name:
Neuronal acetylcholine receptor subunit alpha-7
Synonyms:
Cholinergic, Nicotinic Alpha7 | Cholinergic, Nicotinic Alpha7/5-HT3 | Neuronal acetylcholine receptor subunit alpha-7 | Neuronal acetylcholine receptor subunit alpha-7 (nAChR alpha7) | Neuronal acetylcholine receptor subunit alpha 7 | Neuronal acetylcholine receptor (alpha7 nAChR) | Neuronal acetylcholine receptor subunit alpha-7 (nAChR) | Neuronal acetylcholine receptor | ACHA7_RAT | Chrna7 | Acra7
Type:
Enzyme
Mol. Mass.:
56502.44
Organism:
Rat
Description:
Q05941
Residue:
502
Sequence:
MCGGRGGIWLALAAALLHVSLQGEFQRRLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNMSEYPGVKNVRFPDGQIWKPDILLYNSADERFDATFHTNVLVNASGHCQYLPPGIFKSSCYIDVRWFPFDVQQCKLKFGSWSYGGWSLDLQMQEADISSYIPNGEWDLMGIPGKRNEKFYECCKEPYPDVTYTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLRYHHHDPDGGKMPKWTRIILLNWCAWFLRMKRPGEDKVRPACQHKPRRCSLASVELSAGAGPPTSNGNLLYIGFRGLEGMHCAPTPDSGVVCGRLACSPTHDEHLMHGAHPSDGDPDLAKILEEVRYIANRFRCQDESEVICSEWKFAACVVDRLCLMAFSVFTIICTIGILMSAPNFVEAVSKDFA
  
Inhibitor
Name:
BDBM10759
Synonyms:
2-acetoxyethyl(trimethyl)ammonium;perchlorate | 2-acetoxyethyl(trimethyl)ammonium;bromide | acetylcholine chloride | cid_6060 | CHEMBL667 | [2-(acetyloxy)ethyl]trimethylazanium | acetylcholine | US10667515, Compound ACh
Type:
Small Organic Molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
Search PDB for entries with ligand similarity: