Reaction Details Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM50425201
Substrate
n/a
Meas. Tech.
ChEMBL_937789 (CHEMBL2318043)
Ki
0.090000±n/a nM
Citation
 Morellato, L; Lefas-Le Gall, M; Langlois, M; Caignard, DH; Renard, P; Delagrange, P; Mathé-Allainmat, M Synthesis of new N-(arylcyclopropyl)acetamides and N-(arylvinyl)acetamides as conformationally-restricted ligands for melatonin receptors. Bioorg Med Chem Lett 23:430-4 (2012) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50425201
Synonyms:
CHEMBL2314257
Type:
Small organic molecule
Emp. Form.:
C15H15NO2
Mol. Mass.:
241.2851
SMILES:
COc1ccc2ccccc2c1\C=C\NC(C)=O
Structure:
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