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Target
D-amino-acid oxidase
Ligand
BDBM50146456
Substrate
n/a
Meas. Tech.
ChEMBL_938788 (CHEMBL2327932)
IC50
6269000±n/a nM
Citation
 Katane, M; Osaka, N; Matsuda, S; Maeda, K; Kawata, T; Saitoh, Y; Sekine, M; Furuchi, T; Doi, I; Hirono, S; Homma, H Identification of novel D-amino acid oxidase inhibitors by in silico screening and their functional characterization in vitro. J Med Chem 56:1894-907 (2013) [PubMed]  Article 
Target
Name:
D-amino-acid oxidase
Synonyms:
D-amino-acid oxidase (DAAO) | DAAO | OXDA_HUMAN | DAO | DAMOX
Type:
Homodimer
Mol. Mass.:
39476.06
Organism:
Human
Description:
P14920
Residue:
347
Sequence:
MRVVVIGAGVIGLSTALCIHERYHSVLQPLDIKVYADRFTPLTTTDVAAGLWQPYLSDPNNPQEADWSQQTFDYLLSHVHSPNAENLGLFLISGYNLFHEAIPDPSWKDTVLGFRKLTPRELDMFPDYGYGWFHTSLILEGKNYLQWLTERLTERGVKFFQRKVESFEEVAREGADVIVNCTGVWAGALQRDPLLQPGRGQIMKVDAPWMKHFILTHDPERGIYNSPYIIPGTQTVTLGGIFQLGNWSELNNIQDHNTIWEGCCRLEPTLKNARIIGERTGFRPVRPQIRLEREQLRTGPSNTEVIHNYGHGGYGLTIHWGCALEAAKLFGRILEEKKLSRMPPSHL
  
Inhibitor
Name:
BDBM50146456
Synonyms:
(2E)-3-(3-hydroxyphenyl)prop-2-enoic acid | trans-3-coumaric acid | (2E)-3-(3-hydroxyphenyl)-2-propenoic acid | (2E)-3-(3-hydroxyphenyl)acrylic acid | (E)-3-(3-hydroxyphenyl)-2-propenoic acid | 3-Coumaric acid | trans-3-Hydroxycinnamate | CHEMBL98521
Type:
Small organic molecule
Emp. Form.:
TBD
Mol. Mass.:
TBD
SMILES:
TBD
Structure:
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