Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50195530
Substrate
n/a
Meas. Tech.
ChEMBL_949032 (CHEMBL2343202)
Ki
3797±n/a nM
Citation
 Manca, I; Mastinu, A; Olimpieri, F; Falzoi, M; Sani, M; Ruiu, S; Loriga, G; Volonterio, A; Tambaro, S; Bottazzi, ME; Zanda, M; Pinna, GA; Lazzari, P Novel pyrazole derivatives as neutral CB1 antagonists with significant activity towards food intake. Eur J Med Chem 62:256-69 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_MOUSE | Cannabinoid CB2 receptor | Cannabinoid receptor | Cannabinoid receptor 2 | Cnr2 | mCB2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38220.43
Organism:
MOUSE
Description:
P47936
Residue:
347
Sequence:
MEGCRETEVTNGSNGGLEFNPMKEYMILSSGQQIAVAVLCTLMGLLSALENMAVLYIILSSRRLRRKPSYLFISSLAGADFLASVIFACNFVIFHVFHGVDSNAIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALCVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHRHVATLAEHQDRQVPGIARMRLDVRLAKTLGLVLAVLLICWFPALALMGHSLVTTLSDQVKEAFAFCSMLCLVNSMVNPIIYALRSGEIRSAAQHCLIGWKKYLQGLGPEGKEEGPRSSVTETEADVKTT
  
Inhibitor
Name:
BDBM50195530
Synonyms:
5-(4-chlorophenyl)-3-[(E)-2-cyclohexylethenyl]-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole | CHEMBL386832
Type:
Small organic molecule
Emp. Form.:
C24H23Cl3N2
Mol. Mass.:
445.812
SMILES:
Cc1c(\C=C\C2CCCCC2)nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Structure:
Search PDB for entries with ligand similarity: