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Target
Cannabinoid receptor 1
Ligand
BDBM50431806
Substrate
n/a
Meas. Tech.
ChEMBL_951850 (CHEMBL2353263)
Ki
>40000±n/a nM
Citation
 Alvarado, M; Decara, J; Luque, MJ; Hernandez-Folgado, L; Gómez-Cañas, M; Gómez-Ruiz, M; Fernández-Ruiz, J; Elguero, J; Jagerovic, N; Serrano, A; Goya, P; de Fonseca, FR Novel antiobesity agents: synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21. Bioorg Med Chem 21:1708-16 (2013) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50431806
Synonyms:
CHEMBL2347042
Type:
Small organic molecule
Emp. Form.:
C21H21Cl3N2
Mol. Mass.:
407.764
SMILES:
CCCCCCc1cc(-c2ccc(Cl)cc2)n(n1)-c1ccc(Cl)cc1Cl
Structure:
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