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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50435867
Substrate
n/a
Meas. Tech.
ChEMBL_963768 (CHEMBL2395767)
Ki
13±n/a nM
Citation
 Sadeghzadeh, M; Sheibani, S; Ghandi, M; Daha, FJ; Amanlou, M; Arjmand, M; Hasani Bozcheloie, A Synthesis and receptor binding studies of novel 4,4-disubstituted arylalkyl/arylalkylsulfonyl piperazine and piperidine-based derivatives as a new class ofs1 ligands. Eur J Med Chem 64:488-97 (2013) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50435867
Synonyms:
CHEMBL1479800
Type:
Small organic molecule
Emp. Form.:
C18H21BrN2O2S
Mol. Mass.:
409.341
SMILES:
Brc1ccc(CN2CCN(CC2)S(=O)(=O)Cc2ccccc2)cc1
Structure:
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