Reaction Details Report a problem with these data
Target
N-formyl peptide receptor 3
Ligand
BDBM50435939
Substrate
n/a
Meas. Tech.
ChEMBL_963919
EC50
10200±n/a nM
Citation
 Giovannoni, MP; Schepetkin, IA; Cilibrizzi, A; Crocetti, L; Khlebnikov, AI; Dahlgren, C; Graziano, A; Dal Piaz, V; Kirpotina, LN; Zerbinati, S; Vergelli, C; Quinn, MT Further studies on 2-arylacetamide pyridazin-3(2H)-ones: design, synthesis and evaluation of 4,6-disubstituted analogs as formyl peptide receptors (FPRs) agonists. Eur J Med Chem 64:512-28 (2013) [PubMed]  Article  BDB Entry
Target
Name:
N-formyl peptide receptor 3
Synonyms:
FML2_HUMAN
Type:
PROTEIN
Mol. Mass.:
39971.00
Organism:
Homo sapiens (Human)
Description:
ChEMBL_580003
Residue:
353
Sequence:
METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM
  
Inhibitor
Name:
BDBM50435939
Synonyms:
CHEMBL2391437
Type:
Small organic molecule
Emp. Form.:
C18H16BrN3O2S
Mol. Mass.:
418.308
SMILES:
Cc1cc(Cc2cccs2)c(=O)n(CC(=O)Nc2ccc(Br)cc2)n1
Structure:
Search PDB for entries with ligand similarity: