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Target
D(2) dopamine receptor
Ligand
BDBM50061669
Substrate
n/a
Meas. Tech.
ChEMBL_1290721 (CHEMBL3117733)
EC50
0.020000±n/a nM
Citation
 van Wieringen, JP; Shalgunov, V; Janssen, HM; Fransen, PM; Janssen, AG; Michel, MC; Booij, J; Elsinga, PH Synthesis and characterization of a novel series of agonist compounds as potential radiopharmaceuticals for imaging dopamine D2/3 receptors in their high-affinity state. J Med Chem 57:391-410 (2014) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2
Type:
Cell-surface receptors
Mol. Mass.:
50647.10
Organism:
Homo sapiens (Human)
Description:
P14416
Residue:
443
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFLKILHC
  
Inhibitor
Name:
BDBM50061669
Synonyms:
(R)-2-(Benzylamino-methyl)-chroman-7-ol; oxalic acid | CHEMBL134807 | CHEMBL64553
Type:
Small organic molecule
Emp. Form.:
C17H19NO2
Mol. Mass.:
269.3383
SMILES:
Oc1ccc2CC[C@H](CNCc3ccccc3)Oc2c1
Structure:
Search PDB for entries with ligand similarity: